DSC1 Rabbit Polyclonal Antibody, 50ul Peptide Modification enzyme regulation:Regulated by guanine nucleotide

enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

GO annotations related to this gene include actin binding and WW domain binding

Mutations in this gene are associated with mitochondrial complex I deficiency

Suitable for all common instruments and automation equipment

DSC1 Rabbit Polyclonal Antibody, 50ul Peptide Modification enzyme regulation:Regulated by guanine nucleotideThe protein encoded by this gene is a calcium dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members along with the desmogleins are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus a life threatening autoimmune disease is