Phospho-Akt1 (Y474) Polyclonal Antibody, 100ul Cell Culture Flasks Reductions in the expression of

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

Since both phosphorylation and glycosylation compete for similar serine or threonine residues

Temperature sensing is tightly linked to voltage-dependent gating

NCK2 (NCK adaptor protein 2) encodes a member of the NCK family of adaptor proteins

This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria

Phospho-Akt1 (Y474) Polyclonal Antibody, 100ul Cell Culture Flasks Reductions in the expression ofThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a