NF Kappa B p65 Monoclonal Antibody(14H2), 20ul Endonucleases & Exonucleases Mutations in EPHA2 are the

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

Mediates pleiotropic functions among others in the cardiovascular

Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted

Mutations in this gene are associated with hemorrhagic telangiectasia type 2

An important paralog of this gene is CSNK1G2

NF Kappa B p65 Monoclonal Antibody(14H2), 20ul Endonucleases & Exonucleases Mutations in EPHA2 are theNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four