JIP-1 Polyclonal Antibody, 100ul Immune Cell Analysis The protein encoded by KLF7

The protein encoded by KLF7 (Kruppel like factor 7)is a member of the Kruppel-like transcriptional regulator family

However| the biological validity and full-length nature of some variants cannot be determined at this time

May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death

This suggests this gene product may function as a tumor suppressor

Several transcript variants encoding different isoforms have been found for VIPR1

JIP-1 Polyclonal Antibody, 100ul Immune Cell Analysis The protein encoded by KLF7MAPK8IP1 encodes a regulator of the pancreatic beta cell function. C Jun amino terminal kinase interacting protein 1 is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). C Jun amino terminal kinase interacting protein 1 has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells.