MMP1 (Cleaved-Ile271) Rabbit Polyclonal Antibody, 20ul Nucleic Acid Isolation & Purification Mutation in this gene results

Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia

The protein encoded by this gene has a long and a short form

Malonyl-CoA is an intermediate in fatty acid biosynthesis| and also inhibits the transport of fatty acyl CoAs into mitochondria

The protein may act as a co-regulator of transcription along with other transcription factors

subcellular location:Localized to plasma membrane coated pits

MMP1 (Cleaved-Ile271) Rabbit Polyclonal Antibody, 20ul Nucleic Acid Isolation & Purification Mutation in this gene resultsCatalytic activity: Cleavage of the triple helix of collagen at about three quarters of the length of the molecule from the N terminus at 775 Gly Ile 776 in the alpha 1(I) chain. Cleaves synthetic substrates and alpha macroglobulins at bonds where P1' is a hydrophobic residue. cofactor: Binds 2 zinc ions per subunit. cofactor: Binds 4 calcium ions per subunit. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion