DAD1 Rabbit Polyclonal Antibody, 20ul Yeast Expression A pseudogene of this gene

A pseudogene of this gene is found on chromosome 19

This protein thus

which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis

Mutations in this gene have been found in individuals with nephrotic syndrome

mass spectrometry: PubMed:11840567

DAD1 Rabbit Polyclonal Antibody, 20ul Yeast Expression A pseudogene of this geneDAD1 the defender against apoptotic cell death was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature sensitive cells following a shift to the nonpermissive temperature suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in