PI 3-Kinase p85 beta Polyclonal Antibody, 100ul[BT-AP13020] Shakers Read-through transcription between this locus

Read-through transcription between this locus and the ribosomal protein L36a gene has been observed

which prevents receptor maturation and inhibits Notch signaling

The activity of the protein is negatively regulated by its SH3 domain| whereby deletion of the region encoding this domain results in an oncogene

and CDC42 (MIM 116952)

p32 is mainly found in the cytoplasm

PI 3-Kinase p85 beta Polyclonal Antibody, 100ul[BT-AP13020] Shakers Read-through transcription between this locusPhosphatidylinositol 3 kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non protein coding, have been found for this gene.