GPC1 Polyclonal Antibody, 20ul Insect Expression In addition to being ubiquitinated

In addition to being ubiquitinated by the VHL-E3 ligase complex| this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis| glucose metabolism| cell proliferation and metastasis

This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function

The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element

GO annotations related to this gene include peptidoglycan binding and N-acetylmuramoyl-L-alanine amidase activity

Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain

GPC1 Polyclonal Antibody, 20ul Insect Expression In addition to being ubiquitinatedCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.