HP-1 Alpha mouse Monoclonal Antibody(5E3), 20ul DNA Oligo Synthesis The gene encoding CLIP4 maps

The gene encoding CLIP4 maps to human chromosome 2p23

and reduced expression can suppress transforming growth factor-beta induced growth arrest

This protein is similar to the interleukin 1 accessory proteins

Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process

All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding

HP-1 Alpha mouse Monoclonal Antibody(5E3), 20ul DNA Oligo Synthesis The gene encoding CLIP4 mapsThis gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin associated