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FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use A pseudogene of this gene

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FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use A pseudogene of this geneThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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Description

A pseudogene of this gene is found on chromosome 16

Site-specific binding also suggests that 53BP1 and 53BP2 are involved in p53-mediated tumor suppression

This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome

May have a role in regeneration as well as neural plasticity in the adult nervous system

resulting from unregulated expression of the growth factor

FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use A pseudogene of this geneThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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