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ARHGAP12 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos This gene is predicted to

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ARHGAP12 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos This gene is predicted toARHGAP12 (Rho GTPase activating protein 12) encodes a member of a large family of proteins that activate Rho type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ARHGAP12.

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Description

This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor

subunit:Interacts with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation

This gene encodes a member of the amelogenin family of extracellular matrix proteins

which are located in several of this gene's introns

It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure

ARHGAP12 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos This gene is predicted toARHGAP12 (Rho GTPase activating protein 12) encodes a member of a large family of proteins that activate Rho type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ARHGAP12.

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