GFAP Polyclonal Antibody, 100ul Monoclonal Antibodies The encoded protein can phosphorylate

The encoded protein can phosphorylate myelin basic protein and histone in vitro

2000 [PubMed 10673339])

which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains

The protein encoded by this gene is a small GTPase of the Rho-subfamily| which regulates signaling pathways that control diverse cellular functions including cell morphology| migration| endocytosis and cell cycle progression

GFAP Polyclonal Antibody, 100ul Monoclonal Antibodies The encoded protein can phosphorylateGFAP encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.