Smad3(Phospho Ser213) Polyclonal Antibody, 20ul Site-directed Mutagenesis Cyclin D1 has been shown

Cyclin D1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb

Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)

in a histamine-independent manner

The alpha and alpha' chains contain the catalytic site

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors

Smad3(Phospho Ser213) Polyclonal Antibody, 20ul Site-directed Mutagenesis Cyclin D1 has been shownThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of