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IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation Among its related pathways are

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IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation Among its related pathways areIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

Among its related pathways are protein ubiquitylation

Alternate transcriptional splice variants

Members of the F-box protein family| such as FBXL12| are characterized by an approximately 40-amino acid F-box motif

it is not known whether this trimer is composed of one or more than one alpha chain isomer

which is expressed exclusively in hematopoietic cells

IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation Among its related pathways areIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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