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Stathmin-3 Polyclonal Antibody, 100ul Apoptosis & Autophagy The DPC localizes to the

SKU: 40611171012

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PLN141.00 PLN178.00

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Stathmin-3 Polyclonal Antibody, 100ul Apoptosis & Autophagy The DPC localizes to theSTMN3 encodes Stathmin 3 which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha and beta tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript

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Description

The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy

Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP)

This gene likely encodes a member of the secernin family of proteins

CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system

subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ

Stathmin-3 Polyclonal Antibody, 100ul Apoptosis & Autophagy The DPC localizes to theSTMN3 encodes Stathmin 3 which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha and beta tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript

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