ADCY5 Rabbit Polyclonal Antibody, 50ul Centrifugal Filter An important paralog of this

An important paralog of this gene is RNF214

with high regularity

Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy

which can cause excessive production of reactive oxygen species and cell stress

The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1

ADCY5 Rabbit Polyclonal Antibody, 50ul Centrifugal Filter An important paralog of thisThis gene encodes a member of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2