TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 100ul Serological Pipets Defects in this gene are

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

The protein encoded by CNTNAP3 (contactin associated protein-like 3) belongs to the NCP family of cell-recognition molecules

and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction

and norepinephrine

A germline mutation of VHL is the basis of familial inheritance of VHL syndrome

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 100ul Serological Pipets Defects in this gene areCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only