RGDSR Polyclonal Antibody, 100ul Petri Dishes FZD8 is highly expressed in

FZD8 is highly expressed in two human cancer cell lines

A pseudogene has been identified on chromosome 7

The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRAPPC6A

PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways

RGDSR Polyclonal Antibody, 100ul Petri Dishes FZD8 is highly expressed inThis oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras Raf MEK ERK cascade.