LMX1B Polyclonal Antibody, 20ul Cryopreservation The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed to generate the mature peptidase

Alternative splicing results in multiple transcript variants encoding distinct isoforms

GO annotations related to this gene include nucleic acid binding and nucleotide binding

This protein has a sequence similarity to yeast Prp17 protein

also known as FLJ23757

LMX1B Polyclonal Antibody, 20ul Cryopreservation The encoded preproprotein is proteolyticallyLMX1B encodes a member of LIM homeodomain family of proteins containing two N terminal zinc binding LIM domains, 1 homeodomain, and a C terminal glutamine rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail patella syndrome.