F100A Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance During T-cell activation| this protein

During T-cell activation| this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site| suggesting a negative regulatory role in adaptive immune response

Mitogen-activated protein kinase 8 is activated by various cell stimuli

In addition| the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides| localize to promoters and CpG islands| and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2| an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA

but the full-length nature of these variants has not been determined

Translocation partners include PRCC (papillary renal cell carcinoma)

F100A Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance During T-cell activation| this protein