CYLD Polyclonal Antibody, 50ul Peptide Synthesis The protein associates with hamartin

The protein associates with hamartin in a cytosolic complex| possibly acting as a chaperone for hamartin

ectopia lentis

The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

The complex folds various proteins

Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

CYLD Polyclonal Antibody, 50ul Peptide Synthesis The protein associates with hamartinThis gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.