SESN3 Rabbit Polyclonal Antibody, 50ul Cryopreservation It plays a key role

It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta

Stimulates promoter activity in the presence of NFKB2/p49

miscellaneous:The USP6 gene only exists in the primate lineage

Produced in Class 100

This nuclear gene encodes a mitochondrial tRNA-modifying enzyme

SESN3 Rabbit Polyclonal Antibody, 50ul Cryopreservation It plays a key roleThis gene encodes a member of the sestrin family of stress induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC alpha serine threonine protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript