IRAK-1(Phospho Thr209) Polyclonal Antibody, 100ul Syringe Filter Defects in this gene are

Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness

by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-

The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain

GZMH is present in a gene cluster with another member of the granzyme subfamily on chromosome 14

Cytochrome c-type heme lyase encoded by HCCS is an enzyme that covalently links a heme group to the apoprotein of cytochrome c

IRAK-1(Phospho Thr209) Polyclonal Antibody, 100ul Syringe Filter Defects in this gene areThis gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.