IDUA Polyclonal Antibody, 20ul Biochemical Reagents and ADCAIII often referred to

and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5)

and five C2H2-type zinc finger motifs

This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides

IDUA Polyclonal Antibody, 20ul Biochemical Reagents and ADCAIII often referred toThis gene encodes an enzyme that hydrolyzes the terminal alpha L iduronic acid residues of two glycosaminoglycans dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).