Rb Polyclonal Antibody, 100ul[BT-AP07687] Recombinant Ab Production EMR4P is a member of

EMR4P is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration

ADCK2 participates in ATP and nucleotide binding

Transcriptional suppressor

encodes a protein that is a member of the small GTPase superfamily

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

Rb Polyclonal Antibody, 100ul[BT-AP07687] Recombinant Ab Production EMR4P is a member ofThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.