SMG7 Polyclonal Antibody, 20ul Custom Peptide Synthesis and in mouse it has

and in mouse it has been shown to be required for double-stranded RNA induction of these genes

It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage

GO annotations related to this gene include poly(A) RNA binding

but distinct from other isoenzymes of PKC

This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5

SMG7 Polyclonal Antibody, 20ul Custom Peptide Synthesis and in mouse it hasSMG7 encodes protein SMG7 that is essential for nonsense mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C terminal domain interacts with the mRNA decay