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SPY4 Polyclonal Antibody, 100ul Nucleic Acid Amplification The encoded protein shares a

SKU: 37148980986

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SPY4 Polyclonal Antibody, 100ul Nucleic Acid Amplification The encoded protein shares aThis gene encodes a member of a family of cysteine and proline rich proteins. The encoded protein is an inhibitor of the receptor transduced mitogen activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.

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Description

The encoded protein shares a high level of similarity to the rat homolog| and contains 3 C2 domains and a diacylglycerol-binding C1 domain

possibly by acting as GEFs

where ligand-receptor interactions can result in the activation of

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit

by working in concert with TLR4

SPY4 Polyclonal Antibody, 100ul Nucleic Acid Amplification The encoded protein shares aThis gene encodes a member of a family of cysteine and proline rich proteins. The encoded protein is an inhibitor of the receptor transduced mitogen activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.

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