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Na+ CP type II Alpha Polyclonal Antibody, 50ul[BT-AP05752] Liquid Storage Consumables The encoded nuclear protein functions

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Na+ CP type II Alpha Polyclonal Antibody, 50ul[BT-AP05752] Liquid Storage Consumables The encoded nuclear protein functionsVoltage gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN2A encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in SCN2A have been linked to several seizure

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Description

The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation

Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities

P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17

Mutations in this gene result in epimerase-deficiency galactosemia| also referred to as galactosemia type 3| a disease characterized by liver damage| early-onset cataracts| deafness and mental retardation| with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form)

The encoded type 2 transmembrane protein may play a role in inflammatory and immune response

Na+ CP type II Alpha Polyclonal Antibody, 50ul[BT-AP05752] Liquid Storage Consumables The encoded nuclear protein functionsVoltage gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN2A encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in SCN2A have been linked to several seizure

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