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p73(Phospho Tyr99) Polyclonal Antibody, 50ul Gene Synthesis suggesting a role as a

SKU: 36851443514

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p73(Phospho Tyr99) Polyclonal Antibody, 50ul Gene Synthesis suggesting a role as aThis gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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Description

suggesting a role as a transcription factor

and polymorphisms that alter expression of this gene may play a role in carcinogenesis

Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction

which is associated with Leber congenital amaurosis

This protein is processed by caspases 7

p73(Phospho Tyr99) Polyclonal Antibody, 50ul Gene Synthesis suggesting a role as aThis gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many

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