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DOC2A Rabbit Polyclonal Antibody, 50ul Custom DNA Oligos The zinc finger protein 280A

SKU: 36834623172

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DOC2A Rabbit Polyclonal Antibody, 50ul Custom DNA Oligos The zinc finger protein 280AThere are at least two protein isoforms of the Double C2 protein namely alpha (DOC2A) and beta (DOC2B) which contain two C2 like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC 2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+) dependent neurotransmitter release. Alternative splicing results in multiple transcript variants.

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Description

The zinc finger protein 280A contains 4 C2H2-type zinc fingers

where it is transcriptionally regulated by AP-2epsilon and Ets-1

or with the TCF3 (E2A) gene on chromosome 19

This protein has been shown to interact with

and it may be involved in atherogenesis

DOC2A Rabbit Polyclonal Antibody, 50ul Custom DNA Oligos The zinc finger protein 280AThere are at least two protein isoforms of the Double C2 protein namely alpha (DOC2A) and beta (DOC2B) which contain two C2 like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC 2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+) dependent neurotransmitter release. Alternative splicing results in multiple transcript variants.

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