Histone H2A.Z Polyclonal Antibody, 50ul[BT-AP04008] Cellular Function Assays and upregulated in a breast

and upregulated in a breast cancer cell line after estrogen treatment

The protein precursor is further processed into an active mature peptide

This gene is a member of the regulatory factor X gene family| which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain

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Homotetramers consisting of a proteolytically cleaved form of the protein| or type A subunit| exhibit low affinity for heparin and do not interact with the ECM

Histone H2A.Z Polyclonal Antibody, 50ul[BT-AP04008] Cellular Function Assays and upregulated in a breastHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.