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SRY Polyclonal Antibody, 100ul[BT-AP08575] Cytokines Multiple alternatively spliced transcript variants

SKU: 36679980049

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SRY Polyclonal Antibody, 100ul[BT-AP08575] Cytokines Multiple alternatively spliced transcript variantsThis intronless gene encodes a transcription factor that is a member of the high mobility group (HMG) box family of DNA binding proteins. Sex determining region Y protein is the testis determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

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Description

Multiple alternatively spliced transcript variants of this gene have been described

MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al

the processing of p100 being relatively poor

It may play a role in tumorigenesis and metastasis

It is involved in fibrillar network organization| the anchoring of otoconial membranes and cupulae to the neuroepithelia| and likely in sound stimulation resistance

SRY Polyclonal Antibody, 100ul[BT-AP08575] Cytokines Multiple alternatively spliced transcript variantsThis intronless gene encodes a transcription factor that is a member of the high mobility group (HMG) box family of DNA binding proteins. Sex determining region Y protein is the testis determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

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