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PARP-1 (Acetyl-K521) Polyclonal Antibody, 50ul Cell Culture & Maintenance and is found in all

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PARP-1 (Acetyl-K521) Polyclonal Antibody, 50ul Cell Culture & Maintenance and is found in allThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be

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Description

and is found in all non-muscle tissues

which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes

Radial spokes| which are regularly spaced along cilia| sperm| and flagella axonemes| consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein

The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane

The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs| a stretch of highly acidic amino acids and a serine/threonine-rich sequence

PARP-1 (Acetyl-K521) Polyclonal Antibody, 50ul Cell Culture & Maintenance and is found in allThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be

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