Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy Another member of the CHP

Another member of the CHP subfamily

RING1 and RNF2/RING2

It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro

and possesses ubiquitin ligase E3 activity

It is a C-type lectin with mannose binding specificity

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy Another member of the CHPThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma.