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Vav3(Phospho Tyr173) Polyclonal Antibody, 50ul Recombinant Protein Overexpression of this gene is

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Vav3(Phospho Tyr173) Polyclonal Antibody, 50ul Recombinant Protein Overexpression of this gene isThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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Description

Overexpression of this gene is seen in several cancers

and head/neck

integral membrane serine protease

thus functions as a CDK-activating kinase (CAK)

also located on chromosome 10

Vav3(Phospho Tyr173) Polyclonal Antibody, 50ul Recombinant Protein Overexpression of this gene isThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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