F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression Dysregulation of this gene has

Dysregulation of this gene has been associated with the growth and progression of certain cancers

Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified

The long non-coding RNA transcripts interact with a variety of proteins

Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses

GBA3 is a polymorphic pseudogene

F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression Dysregulation of this gene hasThe protein encoded by this gene is cell cycle regulated and has nuclear localization. The C terminal half of the protein shares homology with trypsin like peptidases and it contains a PCNA interacting peptide (PIP) box that is necessary for its co localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects consistent with the demonstrated role for this gene in Simian Virus 40 (SV40)