GRK 2(Phospho Ser685) Polyclonal Antibody, 50ul Recombinant Protein NFYC encodes one subunit of

NFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes

in the presence of Ca+2 and phospholipids

This encoded protein is one of two V1 domain A subunit isoforms and is found in all

|disease:Chromosomal aberrations involving EP300 may be a cause of acute myeloid leukemias

and cell signaling

GRK 2(Phospho Ser685) Polyclonal Antibody, 50ul Recombinant Protein NFYC encodes one subunit ofThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.