DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody, 20ul DNA Fragments Guanine nucleotide exchange factor (GEF)

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B

ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein (ATP binding cassette subfamily C member 12) contains two ATP-binding domains and 12 transmembrane regions

Expressed in atopic dermatitis| allergic contact dermatitis skin| and psoriasis| in both the eptdermis and dermis

2ml Rotor Adapter

It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon

DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody, 20ul DNA Fragments Guanine nucleotide exchange factor (GEF)Catalytic activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). cofactor: Binds 2 magnesium ions per subunit. Residues 239 252 form a flexible loop which appears to affect the polymerase fidelity. Repair polymerase. Conducts "gap filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5' deoxyribose 5 phosphate lyase (dRP lyase) activity. PTM: Methylation by