GPTC8 Polyclonal Antibody, 50ul Molecular Biology and Brooke-Spiegler syndrome

and Brooke-Spiegler syndrome

The protein encoded by this gene is a lymphocyte-expressed ADAM protein

The protein plays a role in immunity| by restricting transmission of foreign DNA such as viruses

One isoform lacks the intermembrane region and is secreted outside the cell

and neonatal respiratory distress

GPTC8 Polyclonal Antibody, 50ul Molecular Biology and Brooke-Spiegler syndromeThe protein encoded by this gene contains an RNA processing domain, a zinc finger domain, a lysine rich region and a serine rich region. A mutation in the serine rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms.