MDC1(Phospho Ser513) Polyclonal Antibody, 100ul Cell Culture The predominant isoform

The predominant isoform

MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases

Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore

The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites| implicating a role in determining and stabilizing dentritic shape during neuron development

the product of myeloproliferative leukemia virus oncogene

MDC1(Phospho Ser513) Polyclonal Antibody, 100ul Cell Culture The predominant isoformThe protein encoded by this gene contains an N terminal forkhead domain, two BRCA1 C terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41 amino acid sequence. The encoded protein is required to activate the intra S phase and G2 M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double strand breaks through its BRCT motifs, and