Smad6 Monoclonal Antibody, 100ul Human Genome Knockout Libraries Transcript variants encoding different isoforms

Transcript variants encoding different isoforms have been identified for this gene

This gene was identified by its oncogenic transforming activity

While this gene is found on chromosome 20

ductus deferens

which includes type 2 integral membrane metallopeptidases

Smad6 Monoclonal Antibody, 100ul Human Genome Knockout Libraries Transcript variants encoding different isoformsThe protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF beta activin signalling. Multiple transcript variants have been found for this gene.