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SH-PTP2 Polyclonal Antibody, 100ul[BT-AP08303] Cell Labeling & Imaging BAM32 is a B cell-associated

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SH-PTP2 Polyclonal Antibody, 100ul[BT-AP08303] Cell Labeling & Imaging BAM32 is a B cell-associatedTyrosine protein phosphatase non receptor type 11 encoded by PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology 2 domains, which function as phospho tyrosine binding domains and mediate the interaction of this PTP with its

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Description

BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation

Belongs to the glycosyl hydrolase 70 family

May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT

while pseudogenes have been identified on chromosomes 11 and 12

acts by ubiquitinating SYK and promoting its proteasomal degradation

SH-PTP2 Polyclonal Antibody, 100ul[BT-AP08303] Cell Labeling & Imaging BAM32 is a B cell-associatedTyrosine protein phosphatase non receptor type 11 encoded by PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology 2 domains, which function as phospho tyrosine binding domains and mediate the interaction of this PTP with its

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