HMG-17 (Acetyl Lys31) Rabbit Polyclonal Antibody, 100ul Centrifugal Filter A chromosomal translocation t(12

A chromosomal translocation t(12

increased chromosomal breakage

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The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex| which activates pre-mRNA splicing and is an integral part of the spliceosome

Members of this family are involved in organ development and left-right asymmetry

HMG-17 (Acetyl Lys31) Rabbit Polyclonal Antibody, 100ul Centrifugal Filter A chromosomal translocation t(12The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMGN1 the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria viruses and fungi.