IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling Its expression peaks at late

Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle

while it is decreased in dendritic cells

as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis

and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter

mouse studies link its function to adenylyl cyclase inhibition

IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling Its expression peaks at lateThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been