Phospho-Bcl-2 (T74) Polyclonal Antibody, 50ul DNA Fragments The encoded protein may be

The encoded protein may be involved in development of the placenta

interacting with many different ligands

May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons

Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling

and second as adhesion receptors

Phospho-Bcl-2 (T74) Polyclonal Antibody, 50ul DNA Fragments The encoded protein may beBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.