Ezrin(Phospho Tyr353) Polyclonal Antibody, 20ul Sample Library Tubes Src homology 2 (SH2) domains

Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events

such as RAPGEF5 (Rap guanine nucleotide exchange factor 5)

and is involved in organization of DNA

It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction

During ciliogenesis

Ezrin(Phospho Tyr353) Polyclonal Antibody, 20ul Sample Library Tubes Src homology 2 (SH2) domainsThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been