CYH2 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction differing only in the translation

differing only in the translation start site used

ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein

Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2

Several transcript variants encoding two different isoforms have been found for this gene

CYH2 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction differing only in the translationThe protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N terminal coiled coil motif a central Sec7 domain and a C terminal pleckstrin homology (PH) domain. The coiled coil motif is involved in homodimerization the Sec7 domain contains guanine nucleotide exchange protein (GEP) activity and the PH domain interacts with phospholipids and is responsible for