Atg16 Polyclonal Antibody, 100ul Cryopreservation SEPT6 encodes four transcript variants

SEPT6 encodes four transcript variants encoding three distinct isoforms

An important paralog of this gene is LRRTM2

Members of this family share a common domain structure that consists of a transcription activation domain

which is a component of the blood clot

forms an integrin that is a receptor for VCAM1

Atg16 Polyclonal Antibody, 100ul Cryopreservation SEPT6 encodes four transcript variantsThe protein encoded by ATG16L1 (autophagy related 16 like 1) is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in ATG16L1 are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for ATG16L1.