INTS2 Polyclonal Antibody, 20ul Plasmid Preparation Ras GTPase-activating protein 3 functions

Ras GTPase-activating protein 3 functions as a negative regulator of the Ras signalling pathway

Transcript variants utilizing alternative polyA sites exist

By sequence homology

Alternate splicing results in multiple transcript variants encoding different isoforms

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INTS2 Polyclonal Antibody, 20ul Plasmid Preparation Ras GTPase-activating protein 3 functionsINTS2 (integrator complex subunit 2) is a subunit of the Integrator complex, which associates with the C terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3 prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690).