Rat Heme Oxygenase 2, HO-2 ELISA Kit, 96T Biochemical Reagents This protein is assembled into

This protein is assembled into a nucleoprotein complex that is involved in the repair of DNA lesions

a soluble form (S-COMT) and a membrane-bound form (MB-COMT)

and also catalyzes the formation of riboflavin 4'

FAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus

The yeast homolog

Rat Heme Oxygenase 2, HO-2 ELISA Kit, 96T Biochemical Reagents This protein is assembled intoHeme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.